1.Li XL, Guo ZT, Wang YD, Chen XY, Liu J, Zhong DF*. Potential role of organic anion transporting polypeptide 1B1 in the selective hepatic uptake of hematoporphyrin monomethyl ethyl ether isomers. Acta Pharmacologica Sinica, 2015, 36: 268-280
2.Zhu YT, Deng P, Zhong DF*. Derivatization methods for LC–MS analysis of endogenous compounds. Bioanalysis, 2015, 7:2557-2581
3.Liu C, Chen ZQ, Zhong K, Li L, Zhu WL, Chen XY, Zhong DF*. Human liver cytochrome P450 enzymes and microsomal thiol methyltransferase are involved in the stereoselective formation and methylation of the pharmacologically active metabolite of clopidogrel. Drug Metabolism and Disposition, 2015, 43: 1632-1641
4.Zhu YT, Li L, Deng P, Chen XY, Zhong DF*. Characterization of TPN729 metabolites in humans usingultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 2016, 117: 217–226
5.Zhang YF, Dai XJ, Yang Y, Chen XY, Wang T, Tang YB, Tsai CY, Chang LW, Chang YT, Zhong DF*. Effects of probenecid and cimetidine on the pharmacokinetics of nemonoxacin in healthy Chinese volunteers. Drug Design, Development and Therapy, 2016, 10: 357-370
6.Zhu YT, Li L, Zhang G, Wan H, Yang CY, Diao XX, Chen XY, Zhang LS, Zhong DF*. Metabolic characterization of pyrotinib in humans by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry. Journal of Chromatography B, 2016, 1033-1034: 117-127
7.Jiang JF, Pang XH, Li L, Dai XJ, Diao XX, Chen XY, Zhong DF*, Wang YW, Chen YW. Effect of N-methyl deuteration on metabolism and pharmacokinetics of enzalutamide. Drug Design, Development and Therapy, 2016, 10: 2181-2191
8.Yu MM, Gao ZW, Dai XJ, Gong H, Zhang LS, Chen XY, Zhong DF*, Sy SKB*. Population pharmacokibetic and covariate analysis of apatinib, an oral tyrosine kinase inhibitor, in healthy volunteers and patients with solid tumors. Clinical Pharmacokinetics, 2017, 56: 65-76
9.Zhang YF, Chen XY, Tang YB, Lu YM, Guo LX, Zhong DF*. Bioequivalence of generic alendronate sodium tablets (70 mg) to Fosamax tablets (70 mg) in fasting, healthy volunteers: a randomized, open-label, three-way, reference-replicated crossover study. Drug Design, Development and Therapy, 2017, 11: 2109-2119
10.Jiang JF, Chen XY, Zhong DF*. Arylacetamide deacetylase is involved in vicagrel bioactivation in humans. Frontiers in Pharmacology, 2017, 8: 846(1-8)
11.Xu Y, Zhang YF, Chen XY, Zhong DF*. CYP3A4 inducer and inhibitor strongly affect the pharmacokinetics of triptolide and its derivative in rats. Acta Pharmacologica Sinica, 2018, 39: 1386-1392
12.Zhang D, Yang CY, Chen XY, Li XL*, Zhong DF*. A bridging immunogenicity assay for monoclonal antibody: case study with SHR-1222. Bioanalysis, 2018, 10: 1115-1117
13.Liu XY, Zhang YF, Chen Q, Zhan Y, Wang QR, Hu CY, Yu C, Guo ZT, Chen XY, Zhong DF*. Pharmacokinetic drug interactions of apatinib with rifampin and itraconazole. Journal of Clinical Pharmacology, 2018, 58: 347-356
14.Liu C, Lu YM, Sun HB, Yang J, Liu YQ, Lai XJ, Gong YC, Liu XF, Li YG, Zhang YF, Chen XY, Zhong DF*. Development and validation of a sensitive and rapid UHPLC-MS/MS method for the simultaneous quantification of the common active and inactive metabolites of vicagrel and clopidogrel in human plasma. Journal of Pharmaceutical and Biomedical Analysis, 2018, 149: 394-402
15.Jiang JF, Chen XY, Zhong DF*. Predominant contribution of carboxylesterase 1 and 2 in hydrolysis of anordrin in human. Xenobiotica, 2018, 48: 533-540
16.Liu C, Zhang YF, Chen WL, Lu YM, Li W, Liu YQ, Lai XJ, Gong YC, Liu XF, Li YG, Chen XY, Li XN, Sun HB*, Yang J*, Zhong DF*. Pharmacokinetics and pharmacokinetic/pharmacodynamic relationship of vicagrel, a novel thienopyridine P2Y12 inhibitor, compared with clopidogrel in healthy Chinese subjects following single oral dosing. European Journal of Pharmaceutical Sciences, 2019, 127: 151-160
17.Liu XY, Wei Li, Zhang YF, Jiang Y, Zhao QY, Zhong DF*. Simultaneous determination of alflutinib and its active metabolite in human plasma using liquid chromatography-tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 2019, 176: 112735
18.Gao YX, Zhang D, Yang CY, Duan XT, Li XL, Zhong DF*. Two validated liquid chromatography-mass spectrometry methods with different pretreatment for the quantification of an anti-CD47 monoclonal antibody in rat and cynomolgus monkey serum comparing with an electrochemiluminescence method. Journal of Pharmaceutical and Biomedical Analysis, 2019, 175: 112792
19.Zhu YT, Teng Z, Li W, Guo LX, Qu XJ, Wang QR, Mao SY, Chen XY, Zhong DF*. Effects of apatinib on the pharmacokinetics of nifedipine and warfarin in patients with advanced solid tumors. Drug Design, Development and Therapy, 2020, 14: 1963-1970
20.Chen ZD, Gao YX, Zhong DF*. Technologies to improve the sensitivity of existing chromatographic methods used for bioanalytical studies. Biomedical Chromatography, 2020, 34: e4798
